Wolf Creek National Fish Hatchery was constructed in 1975. This is one of the most recently constructed hatcheries in the federal hatchery system.

This station currently produces approximately 1,000,000 trout weighing 250,000 pounds annually. In cooperation with the Kentucky Department of Fish and Wildlife Resources, fish are stocked into 115 different public fishing waters in the state. No private waters are stocked. The majority of the fish are stocked in waters controlled by the federal government.